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18-Aug-2017 02:29

At first, all treatments appeared equally efficacious; however, at 6 months’ follow-up, 32% of patients in the CBT group continued to maintain their treatment gains compared with 20% in the imipramine group and 24% in the combined-treatment group.Foa and colleagues randomized patients with OCD to receive in vivo exposure and response prevention, clomipramine, or a combination of both.Surveys of psychologists who treat patients with PTSD show that the majority do not use exposure therapy and most believe that exposure therapy is likely to exacerbate symptoms.The available research literature suggests that exposure-based therapy should be considered the first-line treatment for a variety of anxiety disorders.Theoretical mechanisms of exposure therapy Biologically, the extinction of fear appears to be mediated by N-methyl-d-aspartate receptor activity in the basolateral amygdala, a finding that has led to the use of neuroplasticity compounds such as d-cycloserine to augment exposure.For example, initial exposure to ocean water can be cold.In clinical practice, these approaches appear equally effective; however, most patients and clinicians choose a graded approach because of the personal comfort level.

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Exposure therapy is defined as any treatment that encourages the systematic confrontation of feared stimuli, with the aim of reducing a fearful reaction.

Graded exposure vs flooding Most exposure therapists use a graded approach in which mildly feared stimuli are targeted first, followed by more strongly feared stimuli.



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